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Your dog might be your best friend, but when they potty on your bed, you might not be feeling very warm and fuzzy about them. Fortunately, there’s no need to run out and buy a brand new mattress—cleaning up dog pee, even off of a mattress, is easier than you might think. In this article, we’ll tell you the step by step process for tackling fresh urine, tough stains, and odors so you can sleep peacefully again.

1

Remove any bedding from the mattress.

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  1. Take off any blankets, comforters, and sheets, and throw them into the wash. Wash your bedding right away to avoid any stains from the urine.[1]
    • If the urine is old, treat your bedding with a stain remover before putting it in the wash.
    • Wash your bedding in hot or warm water to sanitize it and clean it completely.
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3

Combine warm water and vinegar to make a cleaning solution.

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7

Sprinkle baking soda over the wet spot.

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  1. Grab your baking soda and sprinkle a thick layer onto your mattress, covering the entire wet spot. You can’t put too much baking soda onto your mattress, so in this case, the more, the better.[10]
    • Baking soda is also naturally absorbent, so it will help soak up any urine that has penetrated deep into the fibers of your mattress.
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10

Use an enzymatic cleaner on urine stains.

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  1. If your mattress still smells like urine or has a dark spot on it, buy an enzymatic cleaner that’s made specifically for pet stains. Spray a liberal amount on the urine spot on the mattress, then wait the recommended amount of time on the bottle (usually 10 to 20 minutes). Blot the cleaner up with a paper towel, then let your mattress air dry again.[14] [15]
    • It’s important to remove the urine smell completely from your mattress. If your dog can still smell their pee on the bed, they might think that it’s a potty spot, and continue to have accidents on it in the future.
11

Protect your mattress with a mattress cover.

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  1. When you have pets or little kids around, accidents happen—it’s just a fact of life. If you want to avoid cleaning urine off your mattress in the future, invest in a mattress cover. These thin plastic covers protect the outside of your mattress, and they’re comfortable to sleep on, too.[16]
    • Be sure you’re buying a mattress cover that fits your specific bed size.
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  • It's essential not to use any harsh chemical cleaners like hydrogen peroxide to clean up pet stains because they could be toxic to your pets. Make sure any cleaner you use is labeled as "non-hazardous."
  • Keep your pets off your bed by spritzing your mattress with a mix of equal parts water and white vinegar along with a few drops of citrus essential oil.
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Expert Interview

Thanks for reading our article! If you’d like to learn more about cleaning up after your pets, check out our in-depth interview with James Sears.

About This Article

Laura Smith
Co-authored by:
House Cleaning Specialist
This article was co-authored by Laura Smith and by wikiHow staff writer, Hannah Madden. Laura Smith is a House Cleaning Specialist and the Owner of All Star Cleaning Services. With over 16 years of experience, her team specializes in providing natural and eco-friendly house cleaning services. All Star Cleaning Services has earned the Association of Residential Cleaning Services International’s (ARCSI) Seal of Approval and maintained an A+ rating with the Better Business Bureau. This article has been viewed 105,978 times.
21 votes - 95%
Co-authors: 7
Updated: February 4, 2025
Views: 105,978
Categories: Dogs | Cleaning
Thanks to all authors for creating a page that has been read 105,978 times.

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